Clinico-Hematological Profile of Hb Q India: An Uncommon Hemoglobin Variant
نویسندگان
چکیده
منابع مشابه
Clinico-hematological profile of megaloblastic anemia.
Subject and Methods Twenty nine children (age range 3 months to 12 years) diagnosed as megaloblastic anemia over a period of three year (March 1993 to March 1996) were prospectively studied. All anemic children admitted with or without bleeding manifestations had their peripheral blood smear examined. Complete hemogram including platelet count and mean corpuscular volume (MCV) were also carried...
متن کاملClinico Hematological Profile of Acute Promyelocytic Leukemia
Background: Acute promyelocytic leukemia (APL) is a unique subtype of acute leukemia’s. It has distinct Cytogenetics, clinical features, and biologic characteristics. Acute promyelocytic leukemia (APL) is caused by an arrest of leukocyte differentiation at the promyelocytic stage. The discovery and elucidation of the molecular pathogenesis for APL has led to first and only targeted therapy for ...
متن کاملElectrospray mass spectrometric characterization of hemoglobin Q (Hb Q-India) and a double mutant hemoglobin S/D in clinical samples.
OBJECTIVES The clinical analysis of hemoglobin by ion exchange chromatography can result in ambiguities in identification of the nature of the globin chain present in patient samples. LC/ESI-MS provides rapid and precise determination of globin chain masses. DESIGN AND METHODS Hemolysate of hemoglobin Q-India and hemoglobin S/D/F have been analyzed using ESI-MS. Tandem-MS has been used to est...
متن کاملHbQ-India associated with microcytosis: An uncommon hemoglobin variant associated with a common hematologic condition.
HbQ-India is a rare alpha chain variant that usually presents in the heterozygous state. Normally, HbQ-India is clinically silent. It becomes symptomatic when present in association with other conditions. We report a case of HbQ-India with concomitant presence of iron deficiency anemia. A 16-year-old female presented with weakness and pallor intermittently for six years. Complete blood count sh...
متن کاملHemoglobin H associated with an uncommon variant of thalassemia trait.
I N 1955 RIGAS ET AL.1 and Gouttas et al.2 independently reported the discovery of a new hemoglobin characterized electrophoretically at pH 8.6 by a more rapid anodal mobility than that of normal adult hemoglobin. This hemoglobin has subsequently been identified by the letter “H.” More recently, “fast” hemoglobins other than “H” have been described. These include hemoglobins J,3 J,4-1#{176} K,5...
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ژورنال
عنوان ژورنال: Indian Journal of Hematology and Blood Transfusion
سال: 2017
ISSN: 0971-4502,0974-0449
DOI: 10.1007/s12288-017-0864-2